Take Home Quiz 1. Be sure to show your calculations in the space
provided.
1. How many microliters are in 0.457 ml? (1 point)
2. Suppose you had 85µl of a protein sample. Of this
12
µl were diluted into 108 µl of water. Of this dilution
25 µl were submitted to Bradford protein assay and produced an OD
0.63. This is a thought question: for pure
molecules, one would use the Lambert-Beer equation and need the
extinction coefficient. But, some biochemical
assays do not contain pure molecules under defined conditions, thereby
require a standard curve.
If you have
been doing this lab, you already have a prior standard curve, where?
a. What is the dilution from the original
sample
that 25 µl measured in Bradford assay represents? (2 points)
b. How much protein is in the original protein
sample?
(3 points)
c. How much protein is left in the original
sample
at the end of the expirment? (2 points)
3. Suppose you had 23 µl of a DNA sample that had 45 nmoles
DNA/ml.
How much would you need to
dilute the sample to get 4 pmoles/ml? (2 points)