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Prem
P. Chapagain, PhD
Assistant
Professor
Department of
Physics
Florida
International University
11200 SW 8th St
CP 204
Miami, FL 33199
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Ph: 305-348-6266
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Fax: 305-348-6700
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Email:
prem.chapagain@fiu.edu
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Research
Highlights: |
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The
Theoretical Biophysics Group at FIU is involved in several research
projects in the area of biological physics. The major projects include
theoretical and computational investigations of protein folding
dynamics, protein
aggregation, and protein engineering. The group
is equipped with
several SGI workstations and two Linux clusters.
In
addition to the thermodynamics and statistical mechanics of protein
folding and aggregation of model peptide systems, I am interested in
investigating the dynamics and photophysical properties of fluorescent
proteins using detailed all-atom molecular dynamics simulations. My
research interests also include broadly related fields of
biological physics such as mathematical modeling of the dynamics of
infectious diseases, self-organization and complexity.
Recent Publications:
T. Steckmann, Z. Awan, B. S. Gerstman, and P.P. Chapagain. "Kinetics of
peptide secondary structure conversion during amyloid-beta protein
fibrillogenesis" . Journal of Theoretical Biology 301, 95-101 (2012). Link
P.P. Chapagain, C.K. Regmi, and W. Castillo "Fluorescent protein barrel fluctuations and oxygen diffusion pathways in mCherry", Journal of Chemical Physics 135, 235101 (2011) [Featured on the cover] Link
P.P. Chapagain, BS Gerstman, YR Bhandari, D. Rimal “Free-
energy landscapes and thermodynamic parameters of complex molecules from
nonequilibrium simulation trajectories”, Physical Review E 83, 061905 (2011). Link
Y. Liu, P.
P. Chapagain, B. S. Gerstman, "Stabilization of Native and Non-native
Structures by Salt Bridges in a Lattice Model of the GCN4 Leucine
Dimer". Journal of Physical Chemistry B 114, 796-803 (2010). Link
More Articles:
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