KALAI MATHEE, MSc, PhD

Founding Chair & Associate Professor

Department of Molecular Microbiology and Infectious Diseases

College of Medicine, Florida International University, Miami, USA

www.fiu.edu/~matheek

FUNDING

No		Project Title		Agency		Project Dates				Amount (Direct Cost)
External Funding as PI
6		Regulation of P. aeruginosa PoxB oxacillinase by AmpR and a two-component system (Role: PI)		NIH-NIAID		04/08 – 03/12				$1,238,000
5		Role of Pseudomonas aeruginosa ß-lactamase genes (Role: PI)		NIH-NIGMS		04/05 – 03/08				$581,287
4		Ginseng as an antibacterial agent against Pseudomonas aeruginosa (Role: PI)		NIH-R15 AREA		02/05 – 01/08				$207,075
3		Regulation of b-lactamase genes of Pseudomonas aeruginosa (Role: PI)		NIH-MBRS SCORE		04/01 – 3/04				$482,402
2		Immuno-modulation by ginseng (Role: PI)		Dansk Droge A/S, Denmark		03/02 – 09/02				$2,052
1		Ginseng as a possible therapeutic agent (Role: PI)		CF Foundaton		04/01 – 07/02				$43,200
External Funding as Co-PI
10		SEI+II: An integrated database approach to genome-scale analysis (Role: Co-PI; PI: Giri Narasimhan)		NIH-NIGMS		04/06 – 03/08				$189,058
9		Microbial community organization and development of a pathogenic microbial consortium (Role: Co-Investigator; PI: L. Richardson)		NIH-MBRS SCORE		02/04 – 01/08				$845,678
8		Research in nanoelectronics and bio-nano sensors (II) (Role: Co-PI: PI: Kinzy Jones)		AFOSR		04/06 – 02/08				$400,000
7		Development of a mold remediation process using hydrogen peroxide catalyzed by Fe(II) Ions (Role: Co-PI; PI: G. Tachiev, FIU HCET)		Environ Protection Agency		08/04 – 03/05				$92,000
6		Effect of ginseng on the expression of virulence factors in Pseudomonas aeruginosa (Role: Mentor; PI: C. Bigger)		NIH-MBRS MARC		04/01 – 12/05				None
5		Mucoid conversion of P. aeruginosa associated with chronic pulmonary infection in patients (Role: Mentor; PI: C. Bigger)		NIH- MBRS RISE: R25 GM61347		04/99 – 12/05				None
4		Training in alternative tropical botanical medicine (Role: Co-PI; PI: B. Bennett)		NIH-NCCAM		01/02 – 12/05				$1,146,485
3		Discovery and characterization of bacterial quorum sensing signals and their inhibitors (Role: Co-PI; PI: C.L. Koh)		Malaysian Research Council		02 – 04				$20,000
2		Investigation for the effect of Chinese herb ginseng, provided by Dansk Droge A/S, on Pseudomonas aeruginosa associated with cystic fibrosis patients (Role: Co-PI; PI: A. Kharazmi)		Dansk Droge A/S, Denmark		08/00 – 07/01				$37,500
1		Molecularbiological and immunobiological strategies for prevention and treatment of P. aeruginosa from chronic lung infection in cystic fibrosis (Role: Co-PI; PI: N. Høiby)		Danish Research Council		01/98 – 12/02				$321,000
	Internal Funding
	10	Cystic fibrosis sputum profiling (Role: PI)	FIU-NIH FREA				08/06 – 12/06		$5,000
	9	Role of Pseudomonas aeruginosa AmpR in transcription regulation of amp genes (Role: PI)	FIU-NIH FREA				07/04 – 12/04		$2,000
	8	Phage Therapy Agents against Pseudomonas aeruginosa biofilms (Role: PI)	FIU – Provost				05/04 – 09/04		$5,000
	7	Phage Therapy Agents against Pseudomonas aeruginosa biofilms – Travel Grant (Role: PI)	FIU-NIH FREA				11/03 – 12/03		$1,000
	6	Topology analysis P. aeruginosa AmpG permease. (Role: PI)	FIU-NIH FREA				10/03 – 12/03		$4,000
	5	Investigation for the effect of Chinese herb ginseng of Pseudomonas aeruginosa (Role: PI)	DSRT and A & S – Bridge Grant				04/02 – 9/02		$20,229
	4	Undocumented soil microbes of Florida – Search for the unseen novel biosensors (Role: Co- PI; PI: K. Jayachandran )	DSRT Seed Grant				04/01 – 12/01		$4,000
	3	Investigation for the effect of Chinese herb ginseng of Pseudomonas aeruginosa (Role: PI)	DSRT Seed Grant				08/00 – 07/01		$6,000
	2	LS50B spectrometer upgrade (Role: PI)	DSRT and A & S				09/99 – 12/00		$7,185
	1	Analysis of alginate promoters that are activated during mucoid conversion of P. aeruginosa associated with chronic pulmonary infection in patients with cystic fibrosis (Role: PI)	FIU- Faculty Development Grant-in-Aid				09/99 – 12/00		$999
	Students/Fellows Funding/Fellowships under Mathee Mentorship
	No	Project Title			Agency			Project Dates			Amount
	26	Diansy Zincke (PhD student) Regulation of the poxAB operon in Pseudomonas aeruginosa			NIH-BRI/MBRS			Summer 2009			$3000
	25	Deepak Balasubramanian (PhD student) Role of AmpR in Pseudomonas aeruginosa pathogenesis			Cystic Fibrosis Foundation			Jan – April 2009			$1500
	24	Raphael Bosse (Undergraduate) Role of PA4157 encoding an IclR-type regulator in Pseudomonas aeruginosa			Cystic Fibrosis Foundation			Jan – April 2009			$1500
	23	Melissa Doud (PhD candidate) Multiplex PCR for pathogen detection			FIU Eugene Pino Center			Fall 2008			$3000
	22	Diansy Zincke (PhD student) Determining the contribution of poxAB genes to ß-lactam resistance			Cystic Fibrosis Foundation			Fall 2008			$1500
	21	Melissa Doud (PhD candidate) Detection of fungal organisms in the cystic fibrosis lung using amplicon length heterogeneity – polymerase chain reaction (LH-PCR)			Cystic Fibrosis Foundation			Fall 2008			$1500
	20	Diansy Zincke (PhD student) Function of the poxAB operon in Pseudomonas aeruginosa			NIH-BRI/MBRS			Summer 2008			$3000
	19	Melissa Doud (PhD candidate) Detection of fungal organisms in the cystic fibrosis lung using amplicon length heterogeneity – polymerase chain reaction (LH-PCR)			NIH-BRI/MBRS			Summer 2008			$3000
	18	Diansy Zincke (PhD student) Regulation of Pseudomonas aeruginosa pox operon involved in oxacillin resistance.			NIH- MBRS RISE			Spring 2008 –			~30 K
	17	Melissa Doud (PhD candidate) Deciphering the complex fungal and eubacterial bommunities			NIH- MBRS RISE			Fall 2005 –			~30 K
	16	Balasubramanian Danajeyan (Visiting Scholar) Exploitation of soil metagenomics for monitoring microbial nitrogen transformation and soil fertility			Dept of Science & Technology, India			Dec 2007 – May 2008			~10 K
	15	Raquel Olavarrieta (Undergraduate) Regulatory circuitry of Pseudomonas aeruginosa ß-lactam resistance			Cystic Fibrosis Foundation			Aug – Dec 2006			$1500
	14	Allison Adonizio (PhD candidate) Inhibition of quorum-sensing controlled virulence in Pseudomonas aeruginosa by southern Florida plant extracts.			Cystic Fibrosis Foundation			April 2006 –April 2007			$1500
	13	Kok-Fai Kong (PhD candidate) Role of Pseudomonas aeruginosa AmpG in ß-lactam resistance.			Cystic Fibrosis Foundation			July – Sept 2005			$1500
	12	Krystal Anson (Undergraduate) Novel method to remediate mold.			McNair Program, FIU			Summer 2005			$5000
	11	Sixto Leal (Undergraduate) Role of Pseudomonas aeruginosa sdaA encoding L-serine deaminase in bacterial pathogenicity.			Cystic Fibrosis Foundation			Jan – Sept 2005			$1500
	10	Robert Sautter (MS candidate) Prc, a novel protease involved in alginate production.			NIH-BRI/MBRS			Summer 2005			$1500
	9	Allison Adonizio (PhD candidate) Anti-quorum sensing agents from south Florida medicinal plants.			NIH-BRI/MBRS			Summer 2005			$3,000
	8	Allison Adonizio (PhD candidate) Anti-quorum sensing agents from south Florida medicinal plants and their potential to attenuate P. aeruginosa pathogenicty			Cystic Fibrosis Foundation			Mar – May 2005			$1,500
	7	Allison Adonizio (PhD candidate) Identification of quorum sensing inhibitors in south Florida medicinal plants.			NIH- MBRS RISE			Summer 2005 – Spring 2008			~30 K
	6	Allison Adonizio (PhD candidate) Identification of quorum sensing inhibitors of south Florida medicinal plants: an understudied aspect of efficacy.			Cystic Fibrosis Foundation			Summer 2005			$1500
	5	Robert Smiddy (Undergraduate) Identification of novel gene involved in mucoid conversion.			NIH- MBRS RISE			Spring 2004 – Fall 2004			~$10,000
	4	Sergio Luna (Undergraduate) Mapping P. aeruginosa amp gene transcripts			NIH-MBRS RISE			Summer 2002 – Spring 2005			~$10,000
	3	Allison Adonizio (PhD candidate) Anti-quorum sensing agents from south Florida medicinal plants			FIU			2005			$1,000
	2	Alian Aguila (Undergraduate) Topology analysis of Pseudomonas aeruginosa AmpG permease.			NIH-MBRS MARC			Spring 2002 – Spring 2003			~$11,000
	1	Damaris Ramos (Undergraduate) Molecular mechanism responsible for mucoid to nonmucoid conversion in Pseudomonas aeruginosa			NIH-MBRS RISE			May 2001 – Dec 2002			~$10,000