Kalai Mathee, MSc, PhD.
Founding Chair and Professor
Department of Molecular Microbiology and Infectious Diseases

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FUNDED RESEARCH
EXTERNAL FUNDING
No.

Project Title

Agency

Project

Amount
(Direct Cost)

17

       

16

Regulation of P. aeruginosa PoxB oxacillinase by AmpR and a two-component
system
(Role:PI)

NIH-NIGMS

04/08 – 03/12

$1,238,000

15

SEI+II: An integrated database approach to genome-scale analysis
(Role: Co-PI; PI: Giri Narasimhan)

NIH-NIGMS

04/06 – 03/08

$189,058

14

Research in nanoelectronics and bio-nano sensors (II)
(Role: Co-PI: PI: Kinzy Jones)

AFOSR

04/06 – 02/08

$400,000

13

Role of Pseudomonas aeruginosa ß-lactamase genes
(Role: PI)

NIH-NIGMS

04/05 – 03/08

$581,287

12

Ginseng as an antibacterial agent against Pseudomonas aeruginosa
(Role: PI)

NIH-R15 AREA

02/05 – 01/08

$207,075

11

Microbial community organization and development of a pathogenic microbial
consortium 
(Role: Co-Investigator; PI: L. Richardson)

NIH-MBRS SCORE

02/04 – 01/08

$845,678

10

Development of a mold remediation process using hydrogen peroxide
catalyzed by Fe(II) Ions
(Role: Co-PI; PI: G. Tachiev, FIU HCET)

Environmental Protection Agency

08/04 – 03/05

$92,000

9

Effect of ginseng on the expression of virulence factors in Pseudomonas
aeruginosa

(Role: Mentor; PI: C. Bigger)

NIH-MBRS MARC

04/01 – 12/05

None

8

Mucoid conversion of P. aeruginosa associated with chronic pulmonary
infection in patients
(Role: Mentor; PI: C. Bigger)

NIH- MBRS RISE: R25 GM61347

04/99 – 12/05

None

7

Training in alternative tropical botanical medicine
(Role: Co-PI; PI: B. Bennett)

NIH-NCCAM

01/02 – 12/05

$1,146,485

6

Regulation of b-lactamase genes of Pseudomonas aeruginosa
(Role: PI)

NIH-MBRS SCORE

04/01 – 3/04

$482,402

5

Discovery and characterization of bacterial quorum sensing signals and their
inhibitors
(Role: Co-PI; PI: C.L. Koh)

Malaysian Research Council

02 – 04

$20,000

4

Immuno-modulation by ginseng
(Role: PI)

Dansk Droge A/S, Denmark

03/02 – 09/02

$2,052

3

Ginseng as a possible therapeutic agent
(Role: PI)

Cystic Fibrosis Foundation

04/01 – 07/02

$43,200

2

Investigation for the effect of Chinese herb ginseng, provided by Dansk Droge A/S,
on Pseudomonas aeruginosa associated with cystic fibrosis patients
(Role: Co-PI; PI: A. Kharazmi)

Dansk Droge A/S, Denmark

08/00 – 07/01

$37,500

1

Molecularbiological and immunobiological strategies for prevention and treatment
of P. aeruginosa from chronic lung infection in cystic fibrosis
(Role: Co-PI; PI: N. Høiby)

Danish Research Council

01/98 – 12/02

$321,000

INTERNAL FUNDING
No.

Project Title

Agency

Project

Amount
(Direct Cost)

11

The airway microbiome in COPD.
(Role: CoPI; PI: Giri Narasimhan, FIU and Adam Wanner, University of Miami)

Florida DOH Challenge Grant

04/10 - 03/12

$748,400
($314,408 FIU Portion)

10

Cystic fibrosis sputum profiling
(Role: PI)

FIU-NIH FREA

08/06 – 12/06

$5,000

9

Role of Pseudomonas aeruginosa AmpR in transcription regulation of amp genes
(Role: PI)

FIU-NIH FREA

07/04 – 12/04

$2,000

8

Phage Therapy Agents against Pseudomonas aeruginosa biofilms
(Role: PI)

FIU – Provost

05/04 – 09/04

$5,000

7

Phage Therapy Agents against Pseudomonas aeruginosa biofilms – Travel Grant
(Role: PI)

FIU-NIH FREA

11/03 – 12/03

$1,000

6

Topology analysis P. aeruginosa AmpG permease.
(Role: PI)

FIU-NIH FREA

10/03 – 12/03

$4,000

5

Investigation for the effect of Chinese herb ginseng of Pseudomonas aeruginosa
(Role: PI)

DSRT and A & S – Bridge Grant

04/02 – 9/02

$20,229

4

Undocumented soil microbes of Florida – Search for the unseen novel biosensors
(Role: Co- PI; PI: K. Jayachandran )

DSRT Seed Grant

04/01 – 12/01

$4,000

3

Investigation for the effect of Chinese herb ginseng of Pseudomonas aeruginosa
(Role: PI)

DSRT Seed Grant

08/00 – 07/01

$6,000

2

LS50B spectrometer upgrade
(Role: PI)

DSRT and
A & S

09/99 – 12/00

$7,185

1

Analysis of alginate promoters that are activated during mucoid conversion of
P. aeruginosa associated with chronic pulmonary infection in patients with cystic
fibrosis
(Role: PI)

FIU- Faculty Development Grant-in-Aid

09/99 – 12/00

$999

STUDENT/FELLOWS FUNDING/FELLOWSHIPS UNDER K. MATHEE MENTORSHIP
No.

Project Title

Agency

Project

Amount
(Direct Cost)

23

Diansy Zincke (PhD student)
Regulation of the poxAB operon in Pseudomonas aeruginosa

NIH-BRI/MBRS

Summer 2009

$3,000

22

Deepak Balasubramanian (PhD student)
Role of AmpR in Pseudomonas aeruginosa pathogenesis

Cystic Fibrosis Foundation

Jan – April 2009

$1,500

21

Raphael Bosse (Undergraduate)
Role of PA4157 encoding an IclR-type regulator in Pseudomonas aeruginosa

Cystic Fibrosis Foundation

Jan – April 2009

$1,500

20

Diansy Zincke (PhD student)
Function of the poxAB operon in Pseudomonas aeruginosa.

NIH-BRI/MBRS

Summer 2008

$3,000

19

Melissa Doud (PhD candidate)
Detection of fungal organisms in the cystic fibrosis lung using amplicon length
heterogeneity – polymerase chain reaction (LH-PCR).

NIH-BRI/MBRS

Summer 2008

$3,000

18

Diansy Zincke (PhD student)
Regulation of Pseudomonas aeruginosa pox operon involved in oxacillin resistance.

NIH- MBRS RISE

Spring 2008 –

~$30,000

17

Melissa Doud (PhD candidate)
Deciphering the complex fungal and eubacterial bommunities.

NIH- MBRS RISE

Fall 2005 –

~$30,000

16

Balasubramanian Danajeyan (Visiting Scholar)
Exploitation of soil metagenomics for monitoring microbial nitrogen transformation
and soil fertility.

Dept of Science & Technology, India

Dec 2007 – May 2008

~$10,000

15

Raquel Olavarrieta (Undergraduate)
Regulatory circuitry of Pseudomonas aeruginosa ß-lactam resistance.

Cystic Fibrosis Foundation

Aug – Dec 2006

$1,500

14

Allison Adonizio (PhD candidate)
Inhibition of quorum-sensing controlled virulence in Pseudomonas aeruginosa
by southern Florida plant extracts.

Cystic Fibrosis Foundation

April  2006 –April 2007

$1,500

13

Kok-Fai Kong (PhD candidate)
Role of Pseudomonas aeruginosa AmpG in ß-lactam resistance.

Cystic Fibrosis Foundation

July – Sept 2005

$1,500

12

Krystal Anson (Undergraduate)
Novel method to remediate mold.

McNair Program, FIU

Summer 2005

$5,000

11

Sixto Leal (Undergraduate)
Role of Pseudomonas aeruginosa sdaA encoding L-serine deaminase in
bacterial pathogenicity.

Cystic Fibrosis Foundation

Jan  –  Sept 2005

$1,500

10

Robert Sautter (MS candidate)
Prc, a novel protease involved in alginate production.

NIH-BRI/MBRS

Summer 2005

$1,500

9

Allison Adonizio (PhD candidate)
Anti-quorum sensing agents from south Florida medicinal plants.

NIH-BRI/MBRS

Summer 2005

$3,000

8

Allison Adonizio (PhD candidate)
Anti-quorum sensing agents from south Florida medicinal plants and their
potential to attenuate P. aeruginosa pathogenicty.

Cystic Fibrosis Foundation

Mar – May 2005

$1,500

7

Allison Adonizio (PhD candidate)
Identification of quorum sensing inhibitors in South Florida medicinal plants.

NIH- MBRS RISE

Summer 2005 – Spring 2008

~$30,000

6

Allison Adonizio (PhD candidate)
Identification of quorum sensing inhibitors of south Florida medicinal plants:
an understudied aspect of efficacy.

Cystic Fibrosis Foundation

Summer 2005

$1,500

5

Robert Smiddy (Undergraduate)
Identification of novel gene involved in mucoid conversion.

NIH- MBRS RISE

Spring 2004 – Fall 2004

~$10,000

4

Sergio Luna (Undergraduate)
Mapping P. aeruginosa amp gene transcripts.

NIH-MBRS RISE

Summer 2002 –  Spring 2005

~$10,000

3

Allison Adonizio (PhD candidate)
Anti-quorum sensing agents from south Florida medicinal plants.

FIU

2005

$1,000

2

Alian Aguila (Undergraduate)
Topology analysis of Pseudomonas aeruginosa AmpG permease.

NIH-MBRS MARC

Spring 2002 – Spring 2003

~$11,000

1

Damaris Ramos (Undergraduate)
Molecular mechanism responsible for mucoid to nonmucoid conversion in
Pseudomonas aeruginosa

NIH-MBRS RISE

May 2001 – Dec 2002

~$10,000


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